Phenergan codeine maximum dose

PHENERGAN ® - PRODUCT INFORMATION

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<strong>Phenergan</strong> Dosage - Drugs Home Page

Promethazine Dosage Guide with

Promethazine: Antidopaminergic effect due to blocking mesolimbic dopamine receptors and alpha-adrenergic receptors in the brain; antihistaminic effect due to blocking H1-receptors Dextromethorphan: Acts on cough center in medulla; derivative of levorphanol Onset: 20 min Duration: 4-6 hr Bioavailability: 25% (PO) Protein Bound: 93% Vd: 12.9-17.7 L/hr Metabolism: Hepatic P450 enzyme CYP2D6 Metabolites: Promethazine sulfoxide and glucuronides (inactive) Excretion: Urine, feces Dialyzable: No The above information is provided for general informational and educational purposes only.

Phenergan Dosage - Drugs Home Page

Promethazine should not be used in children younger than 2 years because it may cause serious (possibly fatal) slow/shallow breathing.


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