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Objectives To reanalyse Smith Kline Beecham’s Study 329 (published by Keller and colleagues in 2001), the primary objective of which was to compare the efficacy and safety of paroxetine and imipramine with placebo in the treatment of adolescents with unipolar major depression.

Restoring Study 329 efficacy and harms of

Restoring Study 329 efficacy and harms of

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Thousands of Americans are seriously injured and die every year from adverse reactions and side effects associated with prescription medications.

Paxil onset of action:

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